Antibiotic Tolerance and Treatment Outcomes in Cystic Fibrosis Methicillin-Resistant Staphylococcus aureus Infections-Reference-Cited by-同舟云学术

Antibiotic Tolerance and Treatment Outcomes in Cystic Fibrosis Methicillin-Resistant Staphylococcus aureus Infections

Published:2023-02-14 Issue:1 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Lu Kuan-Yi¹^ORCID,Wagner Nikki J.¹,Velez Amanda Z.¹,Ceppe Agathe²,Conlon Brian P.¹²^ORCID,Muhlebach Marianne S.²³

Affiliation:

1. Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

2. Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

3. Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

Abstract

Chronic MRSA infections remain challenging to treat in patients with cystic fibrosis (CF). The ability of the bacterial population to survive high concentrations of bactericidal antibiotics, including vancomycin, despite lacking resistance is considered one of the main reasons for treatment failures.

Funder

Cystic Fibrosis Foundation

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.04061-22

Reference31 articles.

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2. Risk factors for persistent methicillin-resistant Staphylococcus aureus infection in cystic fibrosis

3. Association Between Respiratory Tract Methicillin-Resistant Staphylococcus aureus and Survival in Cystic Fibrosis

4. Pulmonary exacerbations are associated with subsequent FEV1 decline in both adults and children with cystic fibrosis

5. Improving the ability of antimicrobial susceptibility tests to predict clinical outcome accurately: Adding metabolic evasion to the equation

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