Recombinase-Aided Amplification Assay for Rapid Detection of Hypervirulent Klebsiella pneumoniae (hvKp) and Characterization of the hvKp Pathotype

Author:

Yan Chao12,Zhou Yao13,Du Shuheng13,Du Bing1,Zhao Hanqing1,Feng Yanling1,Xue Guanhua1,Cui Jinghua1,Gan Lin1,Feng Junxia1,Fan Zheng1,Fu Tongtong1,Xu Ziying1,Zhang Qun1,Zhang Rui1,Cui Xiaohu1,Tian Ziyan1,Chen Yujie1,Zhang Ting24,Huang Lei5,Yuan Jing12ORCID

Affiliation:

1. Department of Bacteriology, Capital Institute of Pediatrics, Beijing, China

2. Children’s Hospital Capital Institute of Pediatrics, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China

3. Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi’an, Shaanxi, China

4. Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing, China

5. Center for Infectious Diseases, the Fifth Medical Center of Chinese PLA General Hospital, Beijing, China

Abstract

Klebsiella pneumoniae is the most common opportunistic bacterial species and a major threat to public health. Since the 1990s, hvKp has received increasing attention from public health officials and infectious disease specialists.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Beijing Municipality

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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