Conjugative IncC Plasmid Entry Triggers the SOS Response and Promotes Effective Transfer of the Integrative Antibiotic Resistance Element SGI1-Reference-Cited by-同舟云学术

Conjugative IncC Plasmid Entry Triggers the SOS Response and Promotes Effective Transfer of the Integrative Antibiotic Resistance Element SGI1

Published:2023-02-14 Issue:1 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Pons Marine C.¹^ORCID,Praud Karine¹,Da Re Sandra²^ORCID,Cloeckaert Axel¹^ORCID,Doublet Benoît¹^ORCID

Affiliation:

1. INRAE, Université de Tours, ISP, Nouzilly, France

2. INSERM, Université de Limoges, CHU de Limoges, RESINFIT, Limoges, France

Abstract

Antimicrobial resistance has become a major public health issue, particularly with the increase of multidrug resistance (MDR) in both animal and human pathogenic bacteria and with the emergence of resistance to medically important antibiotics. The spread between bacteria of successful mobile genetic elements, such as conjugative plasmids and integrative elements conferring multidrug resistance, is the main driving force in the dissemination of acquired antibiotic resistances among Gram-negative bacteria.

Funder

Centre Val-de-Loire administrative region

EC | Horizon 2020 Framework Programme

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02201-22

Reference42 articles.

1. Host Range and Genetic Plasticity Explain the Coexistence of Integrative and Extrachromosomal Mobile Genetic Elements

2. Pathways for horizontal gene transfer in bacteria revealed by a global map of their plasmids