Horizontal Gene Transfer and Loss of Serotype-Specific Genes in Listeria monocytogenes Can Lead to Incorrect Serotype Designations with a Commonly-Employed Molecular Serotyping Scheme-Reference-Cited by-同舟云学术

Horizontal Gene Transfer and Loss of Serotype-Specific Genes in Listeria monocytogenes Can Lead to Incorrect Serotype Designations with a Commonly-Employed Molecular Serotyping Scheme

Published:2023-02-14 Issue:1 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Brown Phillip¹^ORCID,Kucerova Zuzana²,Gorski Lisa³,Chen Yi⁴,Ivanova Mirena⁵^ORCID,Leekitcharoenphon Pimlapas⁵^ORCID,Parsons Cameron⁶^ORCID,Niedermeyer Jeffrey⁶,Jackson James⁶,Kathariou Sophia¹⁶

Affiliation:

1. Department of Plant and Microbial Biology, North Carolina State University, Raleigh, North Carolina, USA

2. Centers for Disease Control and Prevention (CDC), EDLB/DFWED, Atlanta, Georgia, USA

3. U.S. Department of Agriculture, Agricultural Research Service, Western Regional Research Center, Produce Safety and Microbiology Unit, Albany, California, USA

4. Division of Microbiology, Center for Food Safety and Applied Nutrition, Food and Drug Administration, College Park, Maryland, USA

5. Research Group for Genomic Epidemiology, National Food Institute, Technical University of Denmark, Lyngby, Denmark

6. Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, North Carolina, USA

Abstract

Listeria monocytogenes is a foodborne pathogen responsible for severe illness (listeriosis), especially in pregnant women and their fetuses, immunocompromised individuals, and the elderly. Three serotypes, 1/2a, 1/2b, and 4b, account for most human listeriosis, with certain serotype 4b clonal complexes (CCs) overrepresented in human disease.

Funder

U.S. Department of Agriculture

Danish Dairy Research Foundation

Karl Pederson og Hustrus Industrifond

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02745-22

Reference50 articles.

1. Listeria monocytogenes: towards a complete picture of its physiology and pathogenesis