Gut Microbial Succession Patterns and Metabolic Profiling during Pregnancy and Lactation in a Goat Model

Author:

Zhang Ke1,Liu Gongwei1,Wu Yujiang23,Zhang Ting1,Guo Mengmeng4,Lei Yu1,Cao Xi1,Suo Langda23,Brugger Daniel5ORCID,Wang Xiaolong1,Yang Yuxin1,Chen Yulin1

Affiliation:

1. Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, China

2. Institute of Animal Sciences, Tibet Academy of Agricultural and Animal Husbandry Sciences, Lhasa, China

3. Key Laboratory of Animal Genetics and Breeding on Tibetan Plateau, Ministry of Agriculture and Rural Affairs, Lhasa, China

4. Key Laboratory of Animal Biotechnology, Ministry of Agriculture, College of Veterinary Medicine, Northwest A&F University, Yangling, China

5. Institute of Animal Nutrition and Dietetics, Vetsuisse-Faculty, University of Zurich, Zurich, Switzerland

Abstract

Our findings revealed that the activity of Family_XIII_AD3011_group and Corynebacterium is strongly correlated with the beneficial regulation of physiological hormones and metabolic changes during pregnancy and lactation. These findings are key for guiding targeted microbial therapeutic approaches to modulate microbiomes in gestating and lactating mammals.

Funder

Foreign Expert Project of Tibet

The Technology Innovation Guidance Project of Shaanxi

Science and Technology Project of Tibet

China Agricultural Research System

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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