Molecular Epidemiology of HIV-1 Subtype B Infection across Florida Reveals Few Large Superclusters with Metropolitan Origin

Author:

Rich Shannan N.12,Prosperi Mattia C. F.1,Dellicour Simon34ORCID,Vrancken Bram4ORCID,Cook Robert L.12,Spencer Emma C.5,Salemi Marco26ORCID,Mavian Carla26ORCID

Affiliation:

1. Department of Epidemiology, College of Public Health and Health Professions & College of Medicine, University of Florida, Gainesville, Florida, USA

2. Emerging Pathogens Institute, University of Florida, Gainesville, Florida, USA

3. Spatial Epidemiology Lab (SpELL), Université Libre de Bruxelles, Brussels, Belgium

4. Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory for Clinical and Epidemiological Virology, KU Leuven-University of Leuven, Leuven, Belgium

5. Florida Department of Health, Division of Disease Control and Health Protection, Bureau of Communicable Diseases, Tallahassee, Florida, USA

6. Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, Florida, USA

Abstract

The large number of missing phylogenetic linkages in rural Florida counties and among women and Black persons with HIV may impact timely detection of ongoing and emerging transmission clusters and ultimately hinder the success of epidemic elimination goals in Florida.

Funder

Florida Department of Health

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Reference32 articles.

1. Centers for Disease Control and Prevention. 2019. HIV Surveillance Report 2018 [Internet]. [Cited 2019 Dec 18]. http://www.cdc.gov/hiv/library/reports/hiv-surveillance.html.

2. Centers for Disease Control and Prevention. 2019. HIV in the United States and dependent areas [Internet]. [Cited 2019 Dec 18]. https://www.cdc.gov/hiv/pdf/statistics/overview/cdc-hiv-us-ataglance.pdf.

3. Ending the HIV Epidemic

4. Phylogenetic Studies of Transmission Dynamics in Generalized HIV Epidemics

5. Using Molecular HIV Surveillance Data to Understand Transmission Between Subpopulations in the United States

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