Mycoplasma genitalium Protein of Adhesion Suppresses T Cell Activation via CypA-CaN-NFAT Pathway-Reference-Cited by-同舟云学术

Mycoplasma genitalium Protein of Adhesion Suppresses T Cell Activation via CypA-CaN-NFAT Pathway

Published:2023-06-15 Issue:3 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Luo Dan¹²³⁴,Luo Haodang¹²³⁴,Yan Xiaoliang¹²³,Lei Aihua¹²³,He Jun⁴,Liao Yating¹²³,Peng Kailan¹²³,Li Xia¹²³,Ye Youyuan¹²³,Chen Li¹²³,Zeng Zhuo¹²³,Xiao Hua¹²³,Zeng Yanhua¹²³^ORCID

Affiliation:

1. Institute of Pathogenic Biology, Basic Medical School, Hengyang Medical School, University of South China, Hengyang, Hunan, China

2. Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control, Hengyang, Hunan, China

3. Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Hengyang, Hunan, China

4. Department of Clinical Laboratory, the Affiliated Nanhua Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, China

Abstract

Mycoplasma genitalium is a sexually transmitted bacterium that can co-infect with other infections and causes nongonococcal urethritis in males, cervicitis, pelvic inflammatory disease, premature birth, and ectopic pregnancy in women. The adhesion protein of M. genitalium (MgPa) is the primary virulence factor in the complicated pathogenicity of M. genitalium .

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.04503-22

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