Methanogen Levels Are Significantly Associated with Fecal Microbiota Composition and Alpha Diversity in Healthy Adults and Irritable Bowel Syndrome Patients

Author:

Wang Taojun1ORCID,van Dijk Leander1,Rijnaarts Iris123,Hermes Gerben D. A.1,de Roos Nicole M.2,Witteman Ben J. M.24,de Wit Nicole J. W.3,Govers Coen35,Smidt Hauke1ORCID,Zoetendal Erwin G.1

Affiliation:

1. Laboratory of Microbiology, Wageningen University and Research, Wageningen, the Netherlands

2. Division of Human Nutrition and Health, Wageningen University and Research, Wageningen, the Netherlands

3. Wageningen Food and Biobased Research, Wageningen University and Research, Wageningen, the Netherlands

4. Department of Gastroenterology and Hepatology, Hospital Gelderse Vallei, Ede, the Netherlands

5. Cell Biology and Immunology, Wageningen University and Research, Wageningen, the Netherlands

Abstract

Hydrogenotrophic microbes play an essential role in the disposal of hydrogen and the maintenance of the hydrogen balance in gut ecosystems. Their abundances vary between individuals and have been reported to be associated with human gut disorders such as irritable bowel disease.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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