Discrimination of SARS-CoV-2 Omicron Sublineages BA.1 and BA.2 Using a High-Resolution Melting-Based Assay: a Pilot Study-Reference-Cited by-同舟云学术

Discrimination of SARS-CoV-2 Omicron Sublineages BA.1 and BA.2 Using a High-Resolution Melting-Based Assay: a Pilot Study

Published:2022-08-31 Issue:4 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Aoki Akira¹,Adachi Hirokazu²,Mori Yoko¹,Ito Miyabi²,Sato Katsuhiko²,Okuda Kenji²,Sakakibara Toru²³,Okamoto Yoshinori¹,Jinno Hideto¹^ORCID

Affiliation:

1. Faculty of Pharmacy, Meijo University, Tempaku-ku, Nagoya, Japan

2. Aichi Prefectural Institute of Public Health, Nagoya, Japan

3. Chita Health Center, Chita, Aichi, Japan

Abstract

This study seeks to apply a novel high-resolution melting (HRM) assay to identify and discriminate BA.1 and BA.2 sublineages of the SARS-CoV-2 Omicron variant. Variant BA.2 may cause more severe disease than variant BA.1, meaning that identifying this variant is an important step toward improving the care of patients suffering from COVID-19.

Funder

Daiko Foundation

Meijo University

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01367-22

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