Molecular Characterization of the Convergent Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae Strain K1-ST23, Collected in Chile during the COVID-19 Pandemic

Author:

Morales-León Felipe12,Matus-Köhler Maximiliano12,Araya-Vega Pablo1,Aguilera Felipe3,Torres Ignacio3,Vera Rodrigo4,Ibarra Camila4,Venegas Sebastián4,Bello-Toledo Helia1ORCID,González-Rocha Gerardo1ORCID,Opazo-Capurro Andrés1ORCID

Affiliation:

1. Laboratorio de Investigación en Agentes Antibacterianos, Departamento de Microbiología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile

2. Departamento de Farmacia, Facultad de Farmacia, Universidad de Concepción, Concepción, Chile

3. Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile

4. Hospital de Urgencia Asistencia Pública, Santiago de Chile, Chile

Abstract

Klebsiella pneumoniae is a resistant pathogen involved primarily in hospital-acquired infections. This pathogen is characterized by its notorious resistance to last-line antibiotics, such as carbapenems.

Funder

ANID | Fondo Nacional de Desarrollo Científico y Tecnológico

Agencia Nacional de Investigación y Desarrollo

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Reference26 articles.

1. Klebsiella pneumoniae: Going on the Offense with a Strong Defense

2. Population genomics of Klebsiella pneumoniae

3. Antimicrobial Resistance in ESKAPE Pathogens

4. World Health Organization. 2017. Global priority list of antibiotic-resistant bacteria to guide research discovery and development of new antibiotics.

5. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis

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