Characterization of the Sterol 24-C-Methyltransferase Genes Reveals a Network of Alternative Sterol Biosynthetic Pathways in <i>Mucor lusitanicus</i>-Reference-Cited by-同舟云学术

Characterization of the Sterol 24-C-Methyltransferase Genes Reveals a Network of Alternative Sterol Biosynthetic Pathways in Mucor lusitanicus

Published:2023-06-15 Issue:3 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Bauer Kitti¹²,Rafael Bence¹²,Vágó Bernadett¹²,Kiss-Vetráb Sándor¹²,Molnár Anna¹²,Szebenyi Csilla¹²,Varga Mónika¹,Szekeres András¹,Vágvölgyi Csaba¹²,Papp Tamás¹²,Nagy Gábor¹²^ORCID

Affiliation:

1. Department of Microbiology, University of Szeged, Szeged, Hungary

2. ELKH-SZTE Fungal Pathomechanisms Research Group, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary

Abstract

The fungal membrane contains ergosterol instead of cholesterol, which offers a specific point of attack for the defense against pathogenic fungi. Indeed, most antifungal agents target ergosterol or its biosynthesis.

Funder

NKFI | Nemzeti Kutatási, Fejlesztési és Innovaciós Alap

ELKH

Nemzeti Kutatási Fejlesztési és Innovációs Hivatal

Szegedi Tudományegyetem

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00315-23

Reference61 articles.