Humoral and Cellular Immune Responses to Vector, Mix-and-Match, or mRNA Vaccines against SARS-CoV-2 and the Relationship between the Two Immune Responses

Author:

Nam Minjeong1ORCID,Yun Seung Gyu1ORCID,Kim Sang-wook2,Kim Chris Gunwoo3ORCID,Cha Jae Hyun3ORCID,Lee Cheonghwa3ORCID,Kang Seunghyuk3,Park Seul Gi3,Kim Sun Bean4ORCID,Lee Ki-Byung4ORCID,Chung You-Seung4ORCID,Nam Myung-Hyun1ORCID,Lee Chang Kyu1ORCID,Cho Yunjung1ORCID

Affiliation:

1. Department of Laboratory Medicine, Korea University College of Medicine, Korea University Anam Hospital, Seoul, South Korea

2. Gyeryong City Health, Gyeryong-si, Chungcheongnam-do, South Korea

3. Department of Laboratory Medicine, Korea University Anam Hospital, Seoul, South Korea

4. Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Korea University Anam Hospital, Seoul, South Korea

Abstract

There have been few studies that comprehensively evaluated factors affecting immune responses and the correlation between humoral and cellular immune responses after vector, mix-and-match, and mRNA vaccines against SARS-CoV-2. Therefore, we analyzed the effects of age, sex, and the different vaccine regimens on the immune responses to vaccination against SARS-CoV-2.

Funder

Roche Diagnostics Korea

Abbott Diagnostics

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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