Efficient Recovery of Candida auris and Five Other Medically Important Candida Species from Blood Cultures Containing Clinically Relevant Concentrations of Antifungal Agents

Author:

Posteraro Brunella12ORCID,Menchinelli Giulia3,Ivagnes Vittorio1,Cortazzo Venere1,Liotti Flora Marzia3,Falasca Benedetta1,Fiori Barbara3,D’Inzeo Tiziana13,Spanu Teresa13,De Angelis Giulia13,Sanguinetti Maurizio13ORCID

Affiliation:

1. Dipartimento di Scienze Biotecnologiche di Base, Cliniche Intensivologiche e Perioperatorie, Università Cattolica del Sacro Cuore, Roma, Italy

2. Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy

3. Dipartimento di Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy

Abstract

While echinocandins remain the preferred antifungal therapy for candidemia, bloodstream infections caused by C. auris , C. glabrata , or, at a lesser extent, C. parapsilosis may be difficult to treat with these antifungal agents. This is in view of the high propensity of the above-mentioned species to develop antifungal resistance or tolerance during treatment.

Funder

BioMérieux

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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