A Qualitative Comparison of the Abbott SARS-CoV-2 IgG II Quant Assay against Commonly Used Canadian SARS-CoV-2 Enzyme Immunoassays in Blood Donor Retention Specimens, April 2020 to March 2021-Reference-Cited by-同舟云学术

A Qualitative Comparison of the Abbott SARS-CoV-2 IgG II Quant Assay against Commonly Used Canadian SARS-CoV-2 Enzyme Immunoassays in Blood Donor Retention Specimens, April 2020 to March 2021

Published:2022-06-29 Issue:3 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Abe Kento T.¹²,Rathod Bhavisha¹,Colwill Karen²³,Gingras Anne-Claude¹²,Tuite Ashleigh⁴,Robbins Ninette F.⁵,Orjuela Guillermo⁶,Jenkins Craig⁷,Conrod Valerie⁷,Yi Qi-Long⁸⁹,O’Brien Sheila F.⁸⁹^ORCID,Drews Steven J.¹⁰¹¹^ORCID

Affiliation:

1. Lunenfeld-Tanenbaum Research Institute at Mt. Sinai Hospital, Sinai Health, Toronto, Ontario, Canada

2. Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

3. Treadwell Therapeutics, Toronto, Ontario, Canada

4. Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada

5. Scientific Affairs, Abbott Transfusion Medicine, Chicago, Illinois, USA

6. Scientific Affairs, Abbott Transfusion Medicine, Bogotá, Colombia

7. COVID-19 Serological Screening Laboratory, Canadian Blood Services, Ottawa, Ontario, Canada

8. Epidemiology and Surveillance, Canadian Blood Services, Ottawa, Ontario, Canada

9. School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada

10. Canadian Blood Services, Microbiology, Edmonton, Alberta, Canada

11. Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada

Abstract

We describe the qualitative test characteristics of the Abbott SARS-CoV-2 IgG II Quant assay against four other anti-SARS-CoV-2 IgG assays commonly used in Canada. Although there is no gold standard for identifying anti-SARS-CoV-2 seropositivity, aggregate standards can be used to assess seropositivity.

Funder

Abbott Laboratories

Gouvernement du Canada | Canadian Institutes of Health Research

Alberta Innovates

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01134-22

Reference58 articles.

1. A trend of dropping anti‐SARS‐CoV‐2 plaque reduction neutralization test titers over time in Canadian convalescent plasma donors