Efficient and Scalable Process to Produce Novel and Highly Bioactive Purified Cytosolic Crystals from Bacillus thuringiensis-Reference-Cited by-同舟云学术

Efficient and Scalable Process to Produce Novel and Highly Bioactive Purified Cytosolic Crystals from Bacillus thuringiensis

Published:2022-08-31 Issue:4 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Chicca Jeffrey¹,Cazeault Nicholas R.¹,Rus Florentina¹,Abraham Ambily¹,Garceau Carli¹,Li Hanchen¹,Atwa Samar M.²,Flanagan Kelly¹,Soto Ernesto R.¹,Morrison Mary S.³,Gazzola David¹,Hu Yan¹,Liu David R.³,Nielsen Martin K.²,Urban Joseph F.⁴⁵,Ostroff Gary R.¹,Aroian Raffi V.¹^ORCID

Affiliation:

1. Program in Molecular Medicine, UMASS Chan Medical School, Worcester, Massachusetts, USA

2. M.H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, Kentucky, USA

3. Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, USA

4. U.S. Department of Agriculture, Agricultural Research Service, Beltsville Agricultural Research Center, Animal and Parasitic Diseases Laboratory, Beltsville, Maryland, USA

5. U.S. Department of Agriculture, Agricultural Research Service, Beltsville Human Nutrition Research Center, Diet, Genomics and Immunology Laboratory, Beltsville, Maryland, USA

Abstract

Bacillus thuringiensis crystal proteins are widely and safely used as insecticides. Recent studies have shown they also can cure gastrointestinal parasitic worm (nematode) infections when ingested.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

USDA | National Institute of Food and Agriculture

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02356-22

Reference45 articles.

1. An Analysis of the Biopesticide Market Now and Where it is Going

2. Microbial biopesticides for invertebrate pests and their markets in the United States

3. Potential for Bacillus thuringiensis and Other Bacterial Toxins as Biological Control Agents to Combat Dipteran Pests of Medical and Agronomic Importance

4. Insecticidal Activity of Bacillus thuringiensis Proteins against Coleopteran Pests

5. Specificity and Cross-order Activity of Bacillus thuringiensis Pesticidal Proteins

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