The Bacterial Markers of Identification of Invasive CovR/CovS-Inactivated Group A <i>Streptococcus</i>-Reference-Cited by-同舟云学术

The Bacterial Markers of Identification of Invasive CovR/CovS-Inactivated Group A Streptococcus

Published:2022-10-26 Issue:5 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Shi Yong-An¹^ORCID,Chen Tzu-Ching²,Chen Yan-Wen³,Liu Yen-Shan³,Chen Yi-Ywan M.¹³⁴^ORCID,Lai Chih-Ho¹³⁴,Chiu Cheng-Hsun¹⁴^ORCID,Chiang-Ni Chuan¹³⁴⁵^ORCID

Affiliation:

1. Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan

2. Department of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan, Taiwan

3. Department of Microbiology and Immunology, College of Medicine, Chang Gung University, Taoyuan, Taiwan

4. Molecular Infectious Disease Research Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan

5. Department of Orthopedic Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan

Abstract

Necrotizing fasciitis is rapidly progressive and life-threatening; if the initial diagnosis is delayed, deep soft tissue infection can progress to massive tissue destruction and toxic shock syndrome. Group A Streptococcus (GAS) with inactivated mutations in the CovR/CovS two-component regulatory system are related to necrotizing fasciitis and toxic shock syndrome; however, no bacterial marker is available to identify these invasive clinical isolates.

Funder

Chang Gung Memorial Hospital, Linkou

Ministry of Science and Technology, Taiwan

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02033-22

Reference52 articles.

1. Necrotizing Soft-Tissue Infections

2. Streptococcal Infections of Skin and Soft Tissues

3. Molecular Pathogenesis of Necrotizing Fasciitis

4. The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: A tool for distinguishing necrotizing fasciitis from other soft tissue infections*

5. Validation of the laboratory risk indicator for necrotizing fasciitis (LRINEC) score for early diagnosis of necrotizing fasciitis

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Detection of toxigenic M1UK lineage group A Streptococcus clones in Taiwan;Journal of Microbiology, Immunology and Infection;2024-01

2. RopB-regulated SpeB cysteine protease degrades extracellular vesicles-associated streptolysin O and bacterial proteins from group A Streptococcus;Virulence;2023-08-24

3. RopB represses the transcription ofspeBin the absence of SIP in group AStreptococcus;Life Science Alliance;2023-03-31