An Outer Membrane Protein YiaD Contributes to Adaptive Resistance of Meropenem in Acinetobacter baumannii-Reference-Cited by-同舟云学术

An Outer Membrane Protein YiaD Contributes to Adaptive Resistance of Meropenem in Acinetobacter baumannii

Published:2022-04-27 Issue:2 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Han Lei¹^ORCID,Gao Yiyuan¹,Liu Yuqing¹,Yao Siyu¹,Zhong Shuyan¹,Zhang Sirui¹,Wang Jingdan²,Mi Peng¹³,Wen Yurong⁴⁵,Ouyang Zhenlin⁴⁵,Zhang Jing⁶,Al-Shamiri Mona Mohamed¹,Li Pu²,Han Shaoshan⁷

Affiliation:

1. Department of Microbiology and Immunology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center, Xi’an, China

2. School of Public Health, Xi'an Jiaotong University Health Science Center, Xi’an, China

3. Department of Laboratory Medicine, Shaanxi Provincial People’s Hospital, Xi’an, China

4. The First Affiliated Hospital of Xi'an Jiaotong University, Xi’an, China

5. The Key Laboratory of Environment and Genes Related to Disease of Ministry of Education, Xi'an Jiaotong University Health Science Center, Xi’an, China

6. Department of Laboratory Medicine, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China

7. Department of Hepatobiliary Surgery, the First Affiliated Hospital of Xi’an Jiaotong University, Xi'an, China

Abstract

Acinetobacter baumannii can develop various resistance mechanisms to carbapenems. However, the factors involved in the evolutionary process that leads from transition to the sensitive to resistant phenotype are not clear.

Funder

National Natural Science Foundation of China

MOE | Fundamental Research Funds for the Central Universities

Innovative Traning Program for College Students

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00173-22

Reference61 articles.

1. Outer membrane protein A (OmpA) as a potential therapeutic target for Acinetobacter baumannii infection