Analysis of Regulatory Mechanism of AcrB and CpxR on Colistin Susceptibility Based on Transcriptome and Metabolome of Salmonella Typhimurium-Reference-Cited by-同舟云学术

Analysis of Regulatory Mechanism of AcrB and CpxR on Colistin Susceptibility Based on Transcriptome and Metabolome of Salmonella Typhimurium

Published:2023-08-17 Issue:4 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Zhai Ya-Jun¹,Liu Pei-Yi¹,Luo Xing-Wei¹,Liang Jun²,Sun Ya-Wei³,Cui Xiao-Die¹,He Dan-Dan¹,Pan Yu-Shan¹,Wu Hua¹,Hu Gong-Zheng¹^ORCID

Affiliation:

1. College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China

2. Zhengzhou Animal Husbandry Bureau, Zhengzhou, China

3. Henan Institute of Science and Technology, Xinxiang, China

Abstract

Emergence of multidrug-resistant (MDR) Gram-negative (G - ) bacteria have led to the reconsideration of colistin as the last-resort therapeutic option for health care-associated infections. Finding new drug targets and strategies against the spread of MDR G - bacteria are global challenges for the life sciences community and public health.

Funder

MOST | National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00530-23

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Molecular mechanisms related to colistin resistance in Enterobacteriaceae

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