Dynamics of the MRSA Population in a Chilean Hospital: a Phylogenomic Analysis (2000

Dynamics of the MRSA Population in a Chilean Hospital: a Phylogenomic Analysis (2000–2016)

Published:2023-08-17 Issue:4 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Martínez José R. W.¹²,Planet Paul J.³⁴⁵,Spencer-Sandino Maria¹²,Rivas Lina¹²,Díaz Lorena¹²⁶,Moustafa Ahmed M.³⁴⁷,Quesille-Villalobos Ana¹²,Riquelme-Neira Roberto¹²⁸,Alcalde-Rico Manuel¹²⁹,Hanson Blake¹⁰^ORCID,Carvajal Lina P.⁶,Rincón Sandra⁶,Reyes Jinnethe⁶^ORCID,Lam Marusella¹¹,Calderon Juan F.¹²¹³,Araos Rafael¹²^ORCID,García Patricia²¹¹,Arias César A.¹⁴¹⁵¹⁶^ORCID,Munita José M.¹²¹⁷^ORCID

Affiliation:

1. Genomics & Resistant Microbes (GeRM), ICIM, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago, Chile

2. Multidisciplinary Initiative for Collaborative Research On Bacterial Resistance (MICROB-R), Santiago, Chile

3. Division of Pediatric Infectious Diseases, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

4. Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

5. American Museum of Natural History, New York, New York, USA

6. Molecular Genetics and Antimicrobial Resistance Unit, Universidad El Bosque, Bogotá, Colombia

7. Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

8. Núcleo de Investigaciones Aplicadas en Ciencias Veterinarias y Agronómicas, Facultad de Medicina Veterinaria y Agronomía, Universidad de Las Américas, Santiago, Chile

9. Grupo de Resistencia a los Antibióticos en Bacterias Patógenas y Ambientales (GRABPA), Pontificia Univ. Católica de Valparaíso, Valparaiso, Chile

10. Center for Antimicrobial Resistance and Microbial Genomics, Univ. of Texas Health Science Center, McGovern Medical School, Houston, Texas, USA

11. Departamento de Laboratorios Clínicos, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile

12. Centro de Genética y Genómica Instituto de Ciencias e Innovación en Medicina Facultad de Medicina Clínica Alemana Universidad Del Desarrollo, Santiago, Chile

13. Research Center for the Development of Novel Therapeutic Alternatives for Alcohol Use Disorders, Santiago, Chile

14. Division of Infectious Diseases, Houston Methodist Hospital, Houston, Texas, USA

15. Center for Infectious Diseases, Houston Methodist Research Institution, Houston, Texas, USA

16. Department of Medicine, Weill Cornell Medical College, New York, New York, USA

17. Hospital Padre Hurtado, Santiago, Chile

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is a major public health pathogen that disseminates through the emergence of successful dominant clones in specific geographic regions. Knowledge of the dissemination and molecular epidemiology of MRSA in Latin America is scarce and is largely based on small studies or more limited typing techniques that lack the resolution to represent an accurate description of the genomic landscape.

Funder

Agencia Nacional de Investigación y Desarrollo

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | OSC | Common Fund

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.05351-22

Reference48 articles.

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