Use of Recombinant Endolysin to Improve Accuracy of Group B Streptococcus Tests-Reference-Cited by-同舟云学术

Use of Recombinant Endolysin to Improve Accuracy of Group B Streptococcus Tests

Published:2021-09-03 Issue:1 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Matsui Hidehito¹,Uchiyama Jumpei²³^ORCID,Ogata Masaya³,Nasukawa Tadahiro³,Takemura-Uchiyama Iyo³,Kato Shin-ichiro⁴,Murakami Hironobu³,Higashide Masato⁵,Hanaki Hideaki¹

Affiliation:

1. Ōmura Satoshi Memorial Institute, Kitasato University, Tokyo, Japan

2. Department of Bacteriology, Graduate School of Medicine Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan

3. School of Veterinary Medicine, Azabu University, Sagamihara, Kanagawa, Japan

4. Kochi University, Kochi, Japan

5. Kotobiken Medical Laboratories, Inc., Tsukuba, Ibaraki, Japan

Abstract

Endolysin is a bacteriophage-derived enzyme that degrades the peptidoglycan in the cell wall of host bacteria; it could be used as an antimicrobial agent for selectively eliminating specific bacterial genera/species. Group B Streptococcus (GBS) causes neonatal infection via vertical transmission; prenatal GBS screening test, in which enrichment culture is followed by bacterial identification, is used to detect the presence of GBS in pregnant women.

Funder

MEXT | Japan Science and Technology Agency

Azabu University

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/Spectrum.00077-21

Reference40 articles.

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2. Group B Streptococcus ( Streptococcus agalactiae )