Protection Efficacy of Monoclonal Antibodies Targeting Different Regions of Specific SzM Protein from Swine-Isolated Streptococcus equi ssp.zooepidemicusStrains

Author:

Song Haoshuai12,Yuan Chen12,Zhang Yu12,Pan Fei12,Fan Hongjie123ORCID,Ma Zhe123ORCID

Affiliation:

1. MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China

2. Ministry of Agriculture Key Laboratory of Animal Bacteriology, Nanjing, China

3. Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China

Abstract

The swine-isolated SEZ, with its specificszmgene sequence, has impacted the pig feeding industry in China and North America and has led to serious economic loss. Though the SzM protein of SEZ has been proven to be an effective vaccine in preventing infection, most previous studies focused on horse-isolated strains, which have differentszmgene types compared to swine-isolated strains.

Funder

"Young Scholars" Cultivation Program of College of Veterinary Medicine in Nanjing Agricultural University

MOST | National Key Research and Development Program of China

National Natural Science Foundation of China

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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