High-Throughput Profiling of Candida auris Isolates Reveals Clade-Specific Metabolic Differences-Reference-Cited by-同舟云学术

High-Throughput Profiling of Candida auris Isolates Reveals Clade-Specific Metabolic Differences

Published:2023-06-15 Issue:3 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Brandt Philipp¹,Mirhakkak Mohammad H.²,Wagner Lysett¹,Driesch Dominik³,Möslinger Anna¹⁴,Fänder Pauline¹,Schäuble Sascha²,Panagiotou Gianni²,Vylkova Slavena¹^ORCID

Affiliation:

1. Septomics Research Center, Friedrich Schiller University, and Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany

2. Systems Biology and Bioinformatics, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany

3. BioControl Jena, Jena, Germany

4. Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany

Abstract

Four main clades of the emerging, multidrug-resistant human pathogen Candida auris have been identified, and they differ in their susceptibilities to antifungals and disinfectants. Moreover, clade- and strain-specific metabolic differences have been identified, but a comprehensive overview of nutritional characteristics and resistance to various stressors is missing.

Funder

Bundesministerium für Bildung und Forschung

Deutsche Forschungsgemeinschaft

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00498-23

Reference49 articles.

1. Nine Things Genomics Can Tell Us About Candida auris

2. Integrated genomic, epidemiologic investigation of Candida auris skin colonization in a skilled nursing facility