Pesticin-Like Effector VgrG3 cp Targeting Peptidoglycan Delivered by the Type VI Secretion System Contributes to Vibrio cholerae Interbacterial Competition

Author:

Liu Ming1,Zhao Meng-Yu12,Wang Heng1,Wang Zeng-Hang3,Wang Zhao1,Liu Ying1,Li Yin-Peng2,Dong Tao4ORCID,Fu Yang1ORCID

Affiliation:

1. School of Medicine, Southern University of Science and Technology, Shenzhen, China

2. The First Affiliated Hospital, Southern University of Science and Technology, Shenzhen, China

3. State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

4. Department of Immunology and Microbiology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, China

Abstract

The type VI secretion system used by a broad range of Gram-negative bacteria delivers toxic proteins to target adjacent eukaryotic and prokaryotic cells. Diversification of effector proteins determines the complex bacterium-bacterium interactions and impacts the health of hosts and environmental ecosystems in which bacteria reside.

Funder

Shenzhen Science and Technology Program

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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