Coating and Corruption of Human Neutrophils by Bacterial Outer Membrane Vesicles

Author:

du Teil Espina Marines1,Fu Yanyan1,van der Horst Demi1,Hirschfeld Claudia2,López-Álvarez Marina1,Mulder Lianne M.1,Gscheider Costanza1,Haider Rubio Anna1,Huitema Minke3,Becher Dörte2,Heeringa Peter3,van Dijl Jan Maarten1ORCID

Affiliation:

1. Department of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

2. Institute for Microbiology, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany

3. Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Abstract

Severe periodontitis is a dysbiotic inflammatory disease that affects about 15% of the adult population, making it one of the most prevalent diseases worldwide. Importantly, periodontitis has been associated with the development of nonoral diseases, such as rheumatoid arthritis, pancreatic cancer, and Alzheimer’s disease.

Funder

Graduate School of Medical Sciences of the University of Groningen

China Scholarship Council

Deutsche Forschungsgemeinschaft

EC | Horizon 2020 Framework Programme

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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