Functional Characterization of 15 Novel Dense Granule Proteins in Toxoplasma gondii Using the CRISPR-Cas9 System-Reference-Cited by-同舟云学术

Functional Characterization of 15 Novel Dense Granule Proteins in Toxoplasma gondii Using the CRISPR-Cas9 System

Published:2023-02-14 Issue:1 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Zheng Xiao-Nan¹²,Wang Jin-Lei²³,Elsheikha Hany M.⁴^ORCID,Wang Meng²³,Zhang Zhi-Wei²,Sun Li-Xiu²,Wang Xin-Cheng²,Zhu Xing-Quan¹⁵^ORCID,Li Ting-Ting²³

Affiliation:

1. Laboratory of Parasitic Diseases, College of Veterinary Medicine, Shanxi Agricultural University, Taigu, China

2. State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China

3. Institute of Urban Agriculture, Chinese Academy of Agricultural Sciences, Chengdu, China

4. Faculty of Medicine and Health Sciences, School of Veterinary Medicine and Science, University of Nottingham, Loughborough, United Kingdom

5. Key Laboratory of Veterinary Public Health of Higher Education of Yunnan Province, College of Veterinary Medicine, Yunnan Agricultural University, Kunming, China

Abstract

Dense granule proteins (GRAs) play important roles in Toxoplasma gondii pathogenicity. However, the functions of many putative GRAs have not been elucidated.

Funder

National Natural Science Foundation of China

MOST | National Key Research and Development Program of China

The Research Funding from Lanzhou Veterinary Research Institute

The State Key Laboratory of Veterinary Etiological Biology

Shanxi Provincial Agricultural and Rural Research Program

Fundamental Research Funds of the Chinese Academy of Agricultural Sciences

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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