A DNase Type VI Secretion System Effector Requires Its MIX Domain for Secretion-Reference-Cited by-同舟云学术

A DNase Type VI Secretion System Effector Requires Its MIX Domain for Secretion

Published:2022-10-26 Issue:5 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Fridman Chaya Mushka¹,Jana Biswanath¹,Ben-Yaakov Rotem¹,Bosis Eran²^ORCID,Salomon Dor¹^ORCID

Affiliation:

1. Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

2. Department of Biotechnology Engineering, Braude College of Engineering, Karmiel, Israel

Abstract

Specialized protein delivery systems are used during bacterial competition to deploy cocktails of toxins that target conserved cellular components. Although numerous toxins have been revealed, the activity of many remains unknown.

Funder

EC | European Research Council

Israel Science Foundation

Clore Israel Foundation

Council for Higher Education

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02465-22

Reference60 articles.

1. New Players in the Toxin Field: Polymorphic Toxin Systems in Bacteria

2. Polymorphic toxin systems: Comprehensive characterization of trafficking modes, processing, mechanisms of action, immunity and ecology using comparative genomics

3. Marker for type VI secretion system effectors

4. Polymorphic Toxins and Their Immunity Proteins: Diversity, Evolution, and Mechanisms of Delivery

5. A broadly distributed toxin family mediates contact-dependent antagonism between gram-positive bacteria

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