Transmission Dynamics of a Mycobacterium tuberculosis Complex Outbreak in an Indigenous Population in the Colombian Amazon Region

Author:

Pérez-Llanos Francy J.1ORCID,Dreyer Viola12ORCID,Barilar Ivan12,Utpatel Christian12,Kohl Thomas A.12ORCID,Murcia Martha Isabel3,Homolka Susanne1,Merker Matthias124ORCID,Niemann Stefan12ORCID

Affiliation:

1. Molecular and Experimental Mycobacteriology, Research Center Borstel, Borstel, Germany

2. German Center for Infection Research, Hamburg-Lübeck-Borstel-Riems, Germany

3. Grupo MICOBAC-UN, Departamento de Microbiología, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, Colombia

4. Evolution of the Resistome, Research Center Borstel, Borstel, Germany

Abstract

The Colombian Amazon around Puerto Nariño has a high tuberculosis burden with a prevalence of 1,267/100,000 people in 2016. Recently, an outbreak of Mycobacterium tuberculosis complex (MTBC) bacteria among the indigenous populations was identified with classical MTBC genotyping methods.

Funder

Sistema General de Regalias (SGR), Fondo de Ciencia, Tecnología e Innovación del

Deutsche Forschungsgemeinschaft

IPF | Leibniz-Gemeinschaft

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Reference58 articles.

1. World Health Organization. 2020. Global tuberculosis report 2020. World Health Organization, Geneva, Switzerland.

2. Pan American Health Organization. 2018. Tuberculosis in the Americas, 2018. PAHO, Washington, DC.

3. World Health Organization. 2021. Global tuberculosis report 2021. World Health Organization, Geneva, Switzerland.

4. Instituto Nacional de Salud. 2020. Comportamiento de la vigilancia de tuberculosis, Colombia, 2020. Instituto Nacional de Salud, Bogota, Colombia. https://www.ins.gov.co/buscador-eventos/BoletinEpidemiologico/2021_Boletin_epidemiologico_semana_11.pdf.

5. Instituto Nacional de Salud. 2016. Informe Evento Tuberculosis. Instituto Nacional de Salud, Bogota, Colombia. http://www.ins.gov.co/buscador-eventos/Informesdeevento/Tuberculosis%20%202016.pdf.

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