Decreased Efficiency of Neutralizing Antibodies from Previously Infected or Vaccinated Individuals against the B.1.617.2 (Delta) SARS-CoV-2 Variant

Author:

Dimeglio Chloé12ORCID,Herin Fabrice34,Da-Silva Isabelle1,Gernigon Caroline34,Porcheron Marion1,Chapuy-Regaud Sabine12,Izopet Jacques12ORCID

Affiliation:

1. CHU Toulouse, Hôpital Purpan, Virology Laboratory, Toulouse, France

2. INSERM UMR1291 – CNRS UMR5051, Toulouse Institute for Infectious and Inflammatory Diseases (INFINITy), Toulouse, France

3. Occupational Diseases Department, Toulouse University Hospital, Toulouse, France

4. UMR1295, unité mixte INSERM - Université Toulouse III Paul Sabatier, Centre for Epidemiology and Research in Population Health Unit (CERPOP), Toulouse, France

Abstract

Recent studies showed that the neutralizing antibody titer is an important contributor to protection against SARS-CoV-2. With the emergence of new variants, the question arises of maintaining the neutralizing capacities of vaccines and/or of a past infection.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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