Birth Mode Does Not Determine the Presence of Shared Bacterial Strains between the Maternal Vaginal Microbiome and the Infant Stool Microbiome

Author:

Dos Santos Scott J.1ORCID,Shukla Ishika1,Hill Janet E.1ORCID,Money Deborah M.234ORCID,Money Deborah M.,Hill Janet E.,Joseph K.S.,van Schalkwyk Julie E.,Albert Arianne Y.K.,Elwood Chelsea N.,Gantt Soren,Grabowska Kirsten,Hutcheon Jennifer A.,Links Matthew G.,Manges Amee R.,Mitchell-Foster Sheona M.,Dumonceaux Tim J.,Hodgson Zoë G.,Lyons Janet,

Affiliation:

1. Department of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

2. Department of Obstetrics and Gynaecology, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

3. Department of Microbiology and Immunology, Faculty of Science, University of British Columbia, Vancouver, British Columbia, Canada

4. Women’s Health Research Institute, B.C. Women’s Hospital, Vancouver, British Columbia, Canada

Abstract

The importance of the gut microbiome in human health and disease is widely recognized, and there has been a growing appreciation that alterations in gut microbiome composition during a “critical window” of development may impact health in later life. Attempts to correct gut microbiome dysbiosis related to birth mode are underpinned by the assumption that the lack of exposure to maternal vaginal microbes during caesarean delivery is responsible for dysbiosis.

Funder

Gouvernement du Canada | Canadian Institutes of Health Research

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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