Galectin-9 Facilitates Epstein-Barr Virus Latent Infection and Lymphomagenesis in Human B Cells-Reference-Cited by-同舟云学术

Galectin-9 Facilitates Epstein-Barr Virus Latent Infection and Lymphomagenesis in Human B Cells

Published:2023-02-14 Issue:1 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Xu Jing-xiao¹,Zhang Rong²,Huang Dai-jia¹,Tang Ying³,Ping Li-qin⁴,Huang Bi-jun⁵,Huang Hui-qiang⁴,Busson Pierre⁶^ORCID,Li Jiang¹^ORCID

Affiliation:

1. State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Department of Biotherapy, Sun Yat-sen University Cancer Center, Sun Yat-sen University, Guangzhou, China

2. State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Department of Endoscopy and Laser, Sun Yat-sen University Cancer Center, Sun Yat-sen University, Guangzhou, China

3. Institute of Tumor, Guangzhou University of Chinese Medicine, Guangzhou, China

4. State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Department of Medical Oncology, Sun Yat-sen University Cancer Center, Sun Yat-sen University, Guangzhou, China

5. State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, State Key Lab of Oncology in South China, Sun Yat-sen University Cancer Center, Sun Yat-sen University, Guangzhou, China

6. CNRS-UMR 9018-METSY, Gustave Roussy and Université Paris-Saclay, Villejuif, France

Abstract

The cross talk between Epstein-Barr virus (EBV) and the host cell transcriptome assumes important roles in the oncogenesis of EBV-associated malignancies. Here, we first observed that endogenous Gal-9 expression was persistently increased along with an overturned V-type change in antivirus signaling during the immortalization of EBV-transformed B cells.

Funder

National Key R&D Program of China

Key Program of the Guangzhou City Foundation

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.04932-22

Reference50 articles.