A Multi-Laboratory Evaluation of Commercial Monkeypox Virus Molecular Tests

Author:

Erster Oran1ORCID,Levy Itzchak2,Kabat Areej1,Mannasse Batya1,Levy Virginia1,Assraf Hadar1,Azar Roberto1,Ben-Zvi Haim3,Bradenstein Ritta4,Bunder Olga5,Fadeela Ayman6,Keren-Naus Ayelet7,Peretz Avi89ORCID,Roif-Kaminsky Diana10,Saleh Lolu3,Schreiber Licita11,Schwartz Orna12,Shaked-Mishan Pninit13,Sorek Nadav14,Strauss Merav15,Steinberg Rachel7,Treygerman Orit16,Zisman-Rozen Simona17,Yishai Ruth18,Tejman-Yarden Noa18,Mendelson Ella119,Sofer Danit1

Affiliation:

1. Central Virology Laboratory, Public Health Services, Ministry of Health, Chaim Sheba Medical Center, Ramat Gan, Israel

2. Infectious Diseases Unit, Chaim Sheba Medical Center, Ramat Gan, Israel

3. Beilinson-Rabin Medical Center, Petach Tikva, Israel

4. Kaplan Medical Center, Rehovot, Israel

5. Shamir Medical Center, Beer Yaacov Zerifin, Israel

6. Meir Medical Center, Kfar Sava, Israel

7. Soroka Medical Center, Be'er Sheva, Israel

8. The Baruch Padeh Medical Center, Poriya, Tiberias, Israel

9. The Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel

10. Barzilai Medical Center, Ashkelon, Israel

11. Maccabi HealthCare Central Laboratory, Rehovot, Israel

12. Wolfson Medical Center, Holon, Israel

13. Carmel Medical Center, Haifa, Israel

14. Assuta Ashdod University Hospital, Ashdod, Israel

15. Emek Medical Center, Afula, Israel

16. Me’uchedet HealthCare Central Laboratory, Lod, Israel

17. Galilee Medical Center, Nahariya, Israel

18. Department of Laboratories, Public Health Services, Ministry of Health, Jerusalem, Israel

19. School of Public Health, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel

Abstract

To the best of our knowledge, this study is the first methodical evaluation of commercial kits designed for Monkeypox virus detection. This was done by performing the same tests using the same sample set in multiple laboratories, simultaneously, on a national scale.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Reference19 articles.

1. Human Monkeypox: Current State of Knowledge and Implications for the Future

2. Ongoing monkeypox virus outbreak, Portugal, 29 April to 23 May 2022

3. Human monkeypox: an emerging zoonosis

4. A human infection caused by monkeypox virus in Basankusu Territory, Democratic Republic of the Congo;Ladnyj ID;Bull World Health Organ,1972

5. Retrospective Analysis of Monkeypox Infection

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