Paecilomycone Inhibits Quorum Sensing in Gram-Negative Bacteria-Reference-Cited by-同舟云学术

Paecilomycone Inhibits Quorum Sensing in Gram-Negative Bacteria

Published:2023-04-13 Issue:2 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Beenker Wouter A. G.¹,Hoeksma Jelmer¹,Bannier-Hélaouët Marie¹²,Clevers Hans¹²,den Hertog Jeroen¹³^ORCID

Affiliation:

1. Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, The Netherlands

2. Oncode Institute, Hubrecht Institute-KNAW and University Medical Center, Utrecht, The Netherlands

3. Institute Biology Leiden, Leiden University, Leiden, The Netherlands

Abstract

Antibiotics are becoming less effective against bacterial infections due to the evolution of resistance among bacteria. Pseudomonas aeruginosa is a Gram-negative pathogen that causes major health care concerns and is difficult to treat due to its high intrinsic resistance to antimicrobial agents. Therefore, new targets are needed, and an interesting approach is to target quorum sensing (QS).

Funder

KNAW Research Grant

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.05097-22

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