Performance of Conventional Urine Culture Compared to 16S rRNA Gene Amplicon Sequencing in Children with Suspected Urinary Tract Infection-Reference-Cited by-同舟云学术

Performance of Conventional Urine Culture Compared to 16S rRNA Gene Amplicon Sequencing in Children with Suspected Urinary Tract Infection

Published:2021-12-22 Issue:3 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Marshall Christopher W.¹,Kurs-Lasky Marcia²,McElheny Christi L.²,Bridwell Sophia¹,Liu Hui²,Shaikh Nader²

Affiliation:

1. Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin, USA

2. University of Pittsburgh School of Medicine, Children’s Hospital of Pittsburgh, Division of General Academic Pediatrics, Pittsburgh, Pennsylvania, USA

Abstract

Concordance between conventional culture and 16S rRNA gene amplicon sequencing appears to be high. In children with equivocal culture results, 16S rRNA gene results may provide information that may help clarify the diagnosis.

Funder

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01861-21

Reference24 articles.

1. The Clinical Urine Culture: Enhanced Techniques Improve Detection of Clinically Relevant Microorganisms

2. The Female Urinary Microbiome: a Comparison of Women with and without Urgency Urinary Incontinence

3. The female urinary microbiome in urgency urinary incontinence

4. Rapid diagnosis of bacterial meningitis by nanopore 16S amplicon sequencing: A pilot study

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