Direct Attachment with Erythrocytes Augments Extracellular Growth of Pathogenic Mycobacteria-Reference-Cited by-同舟云学术

Direct Attachment with Erythrocytes Augments Extracellular Growth of Pathogenic Mycobacteria

Published:2022-04-27 Issue:2 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Nishiuchi Yukiko¹²^ORCID,Tateishi Yoshitaka³,Hirano Hiroshi⁴,Ozeki Yuriko³,Yamaguchi Takehiro⁵,Miki Mari⁶,Kitada Seigo⁶,Maruyama Fumito²^ORCID,Matsumoto Sohkichi³⁷^ORCID

Affiliation:

1. Toneyama Institute for Tuberculosis Research, Osaka City University Graduate School of Medicine, Toyonaka, Japan

2. Office of Industry-Academia-Government and Community Collaboration, Hiroshima University, Higashi-Hiroshima, Japan

3. Department of Bacteriology, Niigata University Graduate School of Medicine, Niigata, Japan

4. Department of Diagnostic Pathology, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan

5. Department of Pharmacology, Osaka City University Graduate School of Medicine, Osaka, Japan

6. National Hospital Organization, Osaka Toneyama Medical Center, Toyonaka, Japan

7. Laboratory of Tuberculosis, Institute of Tropical Disease, Universitas Airlangga, Surabaya, Indonesia

Abstract

Pathogenic mycobacteria, such as Mycobacterium tuberculosis , Mycobacterium avium subsp. hominissuis (MAH), and Mycobacterium intracellulare , cause pulmonary infections as intracellular parasites of lung macrophages and epithelial cells. Here, using histopathological examinations we found that MAH and M. intracellulare colocalized with erythrocytes in lung infection sites.

Funder

Japan Agency for Medical Research and Development

MEXT | Japan Society for the Promotion of Science

Institute for Fermentation, Osaka

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02454-21

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