Urease of Aspergillus fumigatus Is Required for Survival in Macrophages and Virulence-Reference-Cited by-同舟云学术

Urease of Aspergillus fumigatus Is Required for Survival in Macrophages and Virulence

Published:2023-04-13 Issue:2 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Xiong Zhenzhen¹,Zhang Nan¹,Xu Liru¹,Deng Zhiduo¹,Limwachiranon Jarukitt¹,Guo Yaojie¹,Han Yi¹,Yang Wei²,Scharf Daniel H.¹³⁴^ORCID

Affiliation:

1. Department of Microbiology, School of Basic Medical Sciences, Zhejiang University School of Medicine, Hangzhou, China

2. Department of Biophysics and Department of Neurosurgery, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China

3. The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China

4. Key Laboratory of Immunity and Inflammatory Diseases of Zhejiang Province, Hangzhou, China

Abstract

The development of antifungal drugs is an urgent task, but it has proven to be difficult due to many similarities between fungal and animal cells. Here, we characterized the urease system in A. fumigatus , which depends on nickel for activity.

Funder

National Natural Science Foundation of China

NSFC | NSFC-Zhejiang Joint Fund | 浙江省科学技术厅 | Basic Public Welfare Research Program of Zhejiang Province

Zhejiang University

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.03508-22

Reference78 articles.

1. Aspergillus Infections

2. Global and Multi-National Prevalence of Fungal Diseases—Estimate Precision

3. Burden of hospitalizations over time with invasive aspergillosis in the United States, 2004–2013

Epidemiology and Mortality-Associated Factors of Invasive Fungal Disease in Elderly Patients: A 20-Year Retrospective Study from Southern China

5. Active Surveillance Program to Increase Awareness on Invasive Fungal Diseases: the French RESSIF Network (2012 to 2018)

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Distinct proteomes and allergen profiles appear across the life-cycle stages of Alternaria alternata;Journal of Allergy and Clinical Immunology;2024-08

2. Targeting bacterial nickel transport with aspergillomarasmine A suppresses virulence-associated Ni-dependent enzymes;Nature Communications;2024-05-13

3. Bioactivity and computational studies on the induction of urease inhibition by three Cu(II) complexes with a fluorinated Schiff base and different secondary ligands;Inorganic Chemistry Communications;2024-01

4. Genomic insight into strategy, interaction and evolution of nitrifiers in metabolizing key labile-dissolved organic nitrogen in different environmental niches;Frontiers in Microbiology;2023-12-13

5. Proteomics of Paracoccidioides lutzii: Overview of Changes Triggered by Nitrogen Catabolite Repression;Journal of Fungi;2023-11-12