Methylxanthines Modulate Circadian Period Length Independently of the Action of Phosphodiesterase-Reference-Cited by-同舟云学术

Methylxanthines Modulate Circadian Period Length Independently of the Action of Phosphodiesterase

Published:2023-08-17 Issue:4 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Olivares-Yañez Consuelo¹²,Alessandri María P.¹³,Salas Loreto¹³,Larrondo Luis F.¹³^ORCID

Affiliation:

1. ANID-Millennium Science Initiative Program, Millennium Institute for Integrative Biology (iBio), Santiago, Chile

2. Centro de Biotecnología Vegetal, Facultad de Ciencias de la Vida, Universidad Andrés Bello, Santiago, Chile

3. Departamento de Genética Molecular y Microbiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile

Abstract

Evidence from diverse organisms show that caffeine causes changes in the circadian clock, causing period lengthening. The fungus Neurospora crassa is no exception; here, several methylxanthines such as caffeine, theophylline, and aminophylline cause period lengthening in a concentration-dependent manner.

Funder

Agencia Nacional de Investigación y Desarrollo

Howard Hughes Medical Institute

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.03727-22

Reference55 articles.

1. Circadian rhythms from multiple oscillators: lessons from diverse organisms

2. Modulation of environmental responses of plants by circadian clocks

3. Montenegro-Montero A, Canessa P, Larrondo LF. 2015. Around the fungal clock: recent advances in the molecular study of circadian clocks in neurospora and other fungi, p 107–184. In Friedmann T, Dunlap JC, Goodwin SF (ed), Advances in genetics, vol 92. Academic Press, Cambridge, MA. Available from https://linkinghub.elsevier.com/retrieve/pii/S0065266015000358.

4. Conserved RNA Helicase FRH Acts Nonenzymatically to Support the Intrinsically Disordered Neurospora Clock Protein FRQ

5. Intrinsic disorder is an essential characteristic of components in the conserved circadian circuit

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