Gut Microbiota Contribution to Weight-Independent Glycemic Improvements after Gastric Bypass Surgery

Author:

Hankir Mohammed K.1ORCID,Kovatcheva-Datchary Petia23,Springer Rebecca1,Hoffmann Annett1,Vogel Jörg24,Seyfried Florian1,Arora Tulika5

Affiliation:

1. Department of General, Visceral, Transplantation, Vascular and Pediatric Surgery, University Hospital Wurzburg, Wurzburg, Germany

2. Institute for Molecular Infection Biology, University of Wurzburg, Wurzburg, Germany

3. Department of Pediatrics, University Hospital Wurzburg, Wurzburg, Germany

4. Helmholtz Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research, Wurzburg, Germany

5. Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Abstract

Metabolic surgery remains the most effective treatment modality for severe obesity and its comorbidities, including type 2 diabetes. Roux-en-Y gastric bypass (RYGB) is a commonly performed type of metabolic surgery that reconfigures gastrointestinal anatomy and profoundly remodels the gut microbiota.

Funder

Novo Nordisk Foundation Center for Basic Metabolic Research

Interdisziplinäres Zentrum für Klinische Forschung, Universitätsklinikum Würzburg

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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