The Anticancer Agent 3,3'-Diindolylmethane Inhibits Multispecies Biofilm Formation by Acne-Causing Bacteria and Candida albicans-Reference-Cited by-同舟云学术

The Anticancer Agent 3,3'-Diindolylmethane Inhibits Multispecies Biofilm Formation by Acne-Causing Bacteria and Candida albicans

Published:2022-02-23 Issue:1 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Kim Yong-Guy¹,Lee Jin-Hyung¹,Park Sunyoung¹,Lee Jintae¹^ORCID

Affiliation:

1. School of Chemical Engineering, Yeungnam University, Gyeongsan, Republic of Korea

Abstract

Since indoles are widespread in nature (even in human skin), we hypothesized that indole and its derivatives might control biofilm formation of acne-causing bacteria ( Cutibacterium acnes and Staphylococcus aureus ) and fungal Candida albicans . The present study reports for the first time the antibiofilm and antimicrobial activities of several indoles on C. acnes .

Funder

National Research Foundation of Korea

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02056-21

Reference46 articles.

1. The Complete Genome Sequence of Propionibacterium Acnes , a Commensal of Human Skin

2. Propionibacterium acnes: from Commensal to Opportunistic Biofilm-Associated Implant Pathogen

3. Propionibacterium acnes biofilm – A sanctuary for Staphylococcus aureus?