Raffinose Inhibits Streptococcus mutans Biofilm Formation by Targeting Glucosyltransferase

Author:

Ham So-Young1,Kim Han-Shin2,Cha Eunji1,Lim Taehyeung3,Byun Youngjoo34,Park Hee-Deung15ORCID

Affiliation:

1. School of Civil, Environmental, and Architectural Engineering, Korea University, Seoul, South Korea

2. Division of Biotechnology, College of Environmental and Bioresource Sciences, Jeonbuk National University, Iksan, Jeonbuk, South Korea

3. College of Pharmacy, Korea University, Sejong, South Korea

4. Biomedical Research Center, Korea University Guro Hospital, Seoul, South Korea

5. KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, South Korea

Abstract

Dental caries is the most prevalent infectious disease and is expensive to manage. Dental biofilms can be eliminated via mechanical treatment or inhibited using antibiotics.

Funder

National Research Foundation of Korea

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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