Polyproline Peptide Aggregation with Klebsiella pneumoniae Extracellular Polysaccharides Exposes Biofilm Associated Bacteria-Reference-Cited by-同舟云学术

Polyproline Peptide Aggregation with Klebsiella pneumoniae Extracellular Polysaccharides Exposes Biofilm Associated Bacteria

Published:2022-04-27 Issue:2 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Fleeman Renee M.¹,Davies Bryan W.¹²³^ORCID

Affiliation:

1. Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas, USA

2. Center for Systems and Synthetic Biology, The University of Texas at Austin, Austin, Texas, USA

3. John Ring LaMontagne Center for Infectious Diseases, The University of Texas at Austin, Austin, Texas, USA

Abstract

Klebsiella pneumoniae bacterial infections are a major threat to human health as mortality rates are steadily on the rise. A defining characteristic of K. pneumoniae is the robust polysaccharide capsule that aids in resistance to the human immune system.

Funder

HHS | National Institutes of Health

DOD | Defense Threat Reduction Agency

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02027-21

Reference41 articles.

1. Klebsiella pneumoniaeinfection biology: living to counteract host defences

2. Capsule Polysaccharide Mediates Bacterial Resistance to Antimicrobial Peptides