Porphyromonas gingivalis Gingipains Destroy the Vascular Barrier and Reduce CD99 and CD99L2 Expression To Regulate Transendothelial Migration-Reference-Cited by-同舟云学术

Porphyromonas gingivalis Gingipains Destroy the Vascular Barrier and Reduce CD99 and CD99L2 Expression To Regulate Transendothelial Migration

Published:2023-06-15 Issue:3 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Zou Zhaolei¹,Fang Juan¹,Ma Wanting¹,Guo Junyi¹,Shan Zhongyan¹,Ma Da¹,Hu Qiannan¹,Wen Liling¹,Wang Zhi¹^ORCID

Affiliation:

1. Hospital of Stomatology, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-Sen University, Guangzhou, Guangdong, People’s Republic of China

Abstract

P. gingivalis is associated with a variety of systemic diseases and colonizes in distal locations in the body. Here, we found that P. gingivalis gingipains degrade PECAM-1 to promote bacterial penetration while simultaneously reducing leukocyte TEM capacity.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.04769-22

Reference51 articles.

1. Porphyromonas gingivalis

2. Periodontal diseases

3. Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities

4. Porphyromonas gingivalis Promotes Colorectal Carcinoma by Activating the Hematopoietic NLRP3 Inflammasome

5. Characterization of the O-Glycoproteome of Porphyromonas gingivalis

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