Linkage of Whole Genome Sequencing, Epidemiological, and Clinical Data to Understand the Genetic Diversity and Clinical Outcomes of Shigella flexneri among Men Who Have Sex with Men in England-Reference-Cited by-同舟云学术

Linkage of Whole Genome Sequencing, Epidemiological, and Clinical Data to Understand the Genetic Diversity and Clinical Outcomes of Shigella flexneri among Men Who Have Sex with Men in England

Published:2021-12-22 Issue:3 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Mitchell Holly D.¹²,Thomson Nicholas R.³⁴,Jenkins Claire⁵⁶,Dallman Timothy J.⁵⁶,Painset Anaïs⁵⁶,Kirwan Peter⁵,Delpech Valerie⁵,Mikhail Amy F. W.⁵,Field Nigel¹,Hughes Gwenda²⁵

Affiliation:

1. Centre for Molecular Epidemiology and Translational Research, Institute for Global Health, University College London, London, UK

2. The National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Blood Borne and Sexually Transmitted Infections at University College London, London, UK

3. Parasites and Microbes, Wellcome Trust Sanger Institute, Hinxton, UK

4. Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, London, UK

5. National Infection Service, Public Health England, London, UK

6. The National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Gastrointestinal Infections at University of Liverpool, Liverpool, UK

Abstract

Within the last 2 decades there have been an increasing number of Shigella spp. outbreaks among men who have sex with men (MSM) worldwide. In 2015, Public Health England (PHE) introduced routine whole genome sequencing (WGS) for the national surveillance of Shigella spp.

Funder

National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Gastrointestinal Infections at University of Liverpool

National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Blood Borne and Sexually Transmitted Infections at University College London

Wellcome Trust

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/Spectrum.01213-21

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