Therapeutic Switching of Rafoxanide: a New Approach To Fighting Drug-Resistant Bacteria and Fungi-Reference-Cited by-同舟云学术

Therapeutic Switching of Rafoxanide: a New Approach To Fighting Drug-Resistant Bacteria and Fungi

Published:2023-08-17 Issue:4 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Bendary Mahmoud M.¹^ORCID,Abd El-Hamid Marwa I.²^ORCID,Abousaty Amira I.³,Elmanakhly Arwa R.⁴,Alshareef Walaa A.⁵,Mosbah Rasha A.⁶,Alhomrani Majid⁷⁸,Ghoneim Mohammed M.⁹,Elkelish Amr¹⁰¹¹,Hashim Nada¹²^ORCID,Alamri Abdulhakeem S.⁷⁸,Al-Harthi Helal F.¹³,Safwat Nesreen A.⁴

Affiliation:

1. Department of Microbiology and Immunology, Faculty of Pharmacy, Port Said University, Port Said, Egypt

2. Department of Microbiology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt

3. Department of Microbiology, Faculty of Science, Zagazig University, Zagazig, Egypt

4. Department of Microbiology and Immunology, Faculty of Pharmacy, Modern University for Technology and Information, Cairo, Egypt

5. Department of Microbiology and Immunology, Faculty of Pharmacy, October 6 University, 6th of October, Egypt

6. Infection Control Unit, Zagazig University Hospital, Zagazig, Egypt

7. Department of Clinical Laboratories Sciences, The Faculty of Applied Medical Science, Taif University, Taif, Saudi Arabia

8. Centre of Biomedical Science Research, Deanship of Scientific Research, Taif University, Taif, Saudi Arabia

9. Department of Pharmacy Practice, College of Pharmacy, Al Maarefa University, Ad Diriyah, Saudi Arabia

10. Biology Department, College of Science, Imam Mohammad ibn Saud Islamic University, Riyadh, Saudi Arabia

11. Botany and Microbiology Department, Faculty of Science, Suez Canal University, Ismailia, Egypt

12. Faculty of Medicine, University of Gezira, Wad Medani, Sudan

13. Biology Department, Turabah University College, Taif University, Taif, Saudi Arabia

Abstract

The drug repurposing strategy is an alternative approach to reducing drug development timelines with low cost, especially during outbreaks of disease caused by drug-resistant pathogens. Rafoxanide can disrupt the abilities of bacterial and fungal cells to adapt to stress conditions.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02679-22

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