Detection of Mycobacterium tuberculosis Complex Using the Xpert MTB/RIF Ultra Assay on the Stool of Pediatric Patients in Dushanbe, Tajikistan-Reference-Cited by-同舟云学术

Detection of Mycobacterium tuberculosis Complex Using the Xpert MTB/RIF Ultra Assay on the Stool of Pediatric Patients in Dushanbe, Tajikistan

Published:2023-02-14 Issue:1 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Rekart Michael L.¹,Mun Lidiya²,Aung Aung²,Gomez Diana¹,Mulanda Winston²,Kliescikova Jarmila²,Sitali Norman¹,Rajabov Asliddin³,Azamova Shahnoza³,Pirmahmadzoda Bobojon⁴,Achar Jay⁵,Alvarez Jose Luis⁶,Greig Jane⁶⁷,Cros Philipp du⁷,Sinha Animesh⁶^ORCID

Affiliation:

1. Médecins sans Frontières, Amsterdam, The Netherlands

2. Médecins sans Frontières, Dushanbe, Tajikistan

3. National Tuberculosis Programme, Dushanbe, Tajikistan

4. Dushanbe City TB Center, Dushanbe, Tajikistan

5. Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden

6. Médecins sans Frontières, London, United Kingdom

7. Burnet Institute, Melbourne, Victoria, Australia

Abstract

The importance of this report is that it provides further support for WHO’s recent recommendation that fresh stool is an acceptable sample for GeneXpert TB testing in children, especially small children who often cannot produce an adequate sputum sample. Diagnosing TB in this age group is difficult, and many cases are missed, leading to unacceptable rates of TB illness and death.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.03698-22

Reference16 articles.

1. WHO. 2020. Global tuberculosis report. World Health Organization, Geneva, Switzerland.

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3. WHO. 2021. WHO global list of high burden countries for tuberculosis (TB), TB/HIV and multidrug/rifampicin resistant TB (MDR/RR-TB) 2021–2025. World Health Organization, Geneva, Switzerland.

4. Stop TB Partnership. 2022. Live TB data interactive country dashboard: Tajikistan. https://dashboards.stoptb.org/country-profile.html. Accessed 26 March 2022.

5. The natural history of childhood intra-thoracic tuberculosis: a critical review of literature from the pre-chemotherapy era;Marais BJ;Int J Tuber Lung Dis,2004

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