British Columbia’s Experience after Implementation of the Treponema pallidum Reverse Algorithm and PCR Detection, 2015 to 2020

Author:

Morshed Muhammad12ORCID,Lee Min-Kuang1,Laley Jonathan1,Cook Darrel3ORCID,Mak Annie1,Chahil Navdeep1,Ryan Venessa3,Montgomery Carolyn3,Makaroff Sylvia3,Malleson Sarah3,Arnold Barbra3,Grennan Troy34,Wong Jason3,Krajden Mel12

Affiliation:

1. British Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada

2. Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada

3. Clinical Prevention Services, BC Centre for Disease Control, Vancouver, British Columbia, Canada

4. Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

Abstract

In this study, we summarize the performance characteristics of the algorithm, together with PCR direct detection and epidemiological analysis, and report on syphilis cases identified from 2015 to 2020. This allowed us to paint a complete picture of the outcome of the utilization of the reverse algorithm for diagnosing syphilis cases.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Reference32 articles.

1. Syphilis

2. Public Health Agency of Canada. 2020. Infectious syphilis and congenital syphilis in Canada, 2020. Public Health Agency of Canada, Ottawa, Ontario, Canada. https://www.canada.ca/en/public-health/services/publications/diseases-conditions/infectious-syphilis-congenital-syphilis-canada-2020.html.

3. Centers for Disease Control and Prevention. 2019. National overview—sexually transmitted disease surveillance, 2019. Centers for Disease Control and Prevention, Atlanta, GA. https://www.cdc.gov/std/statistics/2019/overview.htm#Syphilis. Accessed 11 February 2022.

4. BC Centre for Disease Control. 2022. Reportable diseases data dashboard. BC Centre for Disease Control, Vancouver, British Columbia, Canada. http://www.bccdc.ca/health-professionals/data-reports/reportable-diseases-data-dashboard.

5. The Laboratory Diagnosis of Syphilis

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