Rapid Phenotypic Convergence towards Collateral Sensitivity in Clinical Isolates of Pseudomonas aeruginosa Presenting Different Genomic Backgrounds-Reference-Cited by-同舟云学术

Rapid Phenotypic Convergence towards Collateral Sensitivity in Clinical Isolates of Pseudomonas aeruginosa Presenting Different Genomic Backgrounds

Published:2023-02-14 Issue:1 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Hernando-Amado Sara¹^ORCID,López-Causapé Carla²,Laborda Pablo¹,Sanz-García Fernando¹³,Oliver Antonio²^ORCID,Martínez José Luis¹^ORCID

Affiliation:

1. Centro Nacional de Biotecnología, CSIC, Madrid, Spain

2. Servicio de Microbiología, Hospital Universitario Son Espases, Instituto de Investigación Sanitaria Illes Balears, CIBERINFEC, Palma de Mallorca, Spain

3. Departamento de Microbiología, Medicina Preventiva y Salud Pública, Universidad de Zaragoza, Zaragoza, Spain

Abstract

Collateral sensitivity (CS) is a trade-off of antibiotic resistance evolution that could be exploited to design strategies for treating bacterial infections. Clinical application of CS requires it to robustly emerge in different genomic backgrounds.

Funder

MEC | Instituto de Salud Carlos III

Comunidad de Madrid

MCIN/AEI

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02276-22

Reference62 articles.

1. Mechanisms of Antimicrobial Resistance in ESKAPE Pathogens