Molecular Epidemiology of Drug Resistance Genes in Plasmodium falciparum Isolates Imported from Nigeria between 2016 and 2020: Continued Emergence of Fully Resistant <i>Pfdhfr</i> - <i>Pfdhps</i> Alleles-Reference-Cited by-同舟云学术

Molecular Epidemiology of Drug Resistance Genes in Plasmodium falciparum Isolates Imported from Nigeria between 2016 and 2020: Continued Emergence of Fully Resistant Pfdhfr - Pfdhps Alleles

Published:2022-10-26 Issue:5 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Wang Xiaoxiao¹,Zhang Xuan¹,Chen Hualiang¹,Zhang Jiaqi¹,Lu Qiaoyi¹,Ruan Wei¹^ORCID,Ling Feng¹

Affiliation:

1. Zhejiang Provincial Center for Disease Control and Prevention, Zhejiang, People’s Republic of China

Abstract

Monitoring the current resistance to antimalarial drugs is critical to enable timely action to prevent its spread and limit its impact. The high prevalence of wild-type Pfcrt found in our study is an optimistic signal to reevaluate chloroquine (CQ) sensitivity in Nigeria, which is cost-effective and once played a crucial role in the fight against malaria.

Funder

Major Health Science and Technology Projects in Zhejiang Province

Medical Research Program of Zhejiang Province

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00528-22

Reference40 articles.

1. World Health Organization. 2021. World malaria report. World Health Organization, Geneva, Switzerland.

2. World Health Organization. 2020. World malaria report. World Health Organization, Geneva, Switzerland.