Mechanism of Action of Isopropoxy Benzene Guanidine against Multidrug-Resistant Pathogens

Author:

Li Jie123,Zhang Xiufeng123,Han Ning123,Wan Peng123,Zhao Feifei123,Xu Tiantian123,Peng Xianfeng4,Xiong Wenguang123ORCID,Zeng Zhenling123ORCID

Affiliation:

1. Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China

2. National Laboratory of Safety Evaluation (Environmental Assessment) of Veterinary Drugs, South China Agricultural University, Guangzhou, China

3. National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, South China Agricultural University, Guangzhou, China

4. Guangzhou Insighter Biotechnology Co., Ltd., Guangzhou, China

Abstract

As antibiotic discovery stagnates, the world is facing a growing menace from the emergence of bacteria that are resistant to almost all available antibiotics. The key to winning this race is to explore distinctive mechanisms of antibiotics.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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