Mycothiol Peroxidase Activity as a Part of the Self-Resistance Mechanisms against the Antitumor Antibiotic Cosmomycin D-Reference-Cited by-同舟云学术

Mycothiol Peroxidase Activity as a Part of the Self-Resistance Mechanisms against the Antitumor Antibiotic Cosmomycin D

Published:2022-06-29 Issue:3 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Castillo Arteaga Roger D.¹²^ORCID,Garrido Leandro M.²^ORCID,Pedre Brandán³^ORCID,Helmle Irina¹^ORCID,Gross Harald¹⁴^ORCID,Gust Bertolt¹⁴^ORCID,Padilla Gabriel²^ORCID

Affiliation:

1. Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany

2. Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

3. Division of Redox Regulation, DKFZ-ZMBH Alliance, German Cancer Research Center (DKFZ), Heidelberg, Germany

4. German Center for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany

Abstract

Anthracycline compounds are DNA intercalating agents widely used in cancer chemotherapeutic protocols. This work focused on the self-resistance mechanisms developed by the cosmomycin-producing bacterium Streptomyces olindensis .

Funder

Deutscher Akademischer Austauschdienst

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00493-22

Reference54 articles.

1. Adriamycin, 14-hydroxydaimomycin, a new antitumor antibiotic fromS. Peucetius var.caesius

2. Anthracyclines: Selected New Developments

3. Anthracyclines: Molecular Advances and Pharmacologic Developments in Antitumor Activity and Cardiotoxicity

4. Role of liposomal anthracyclines in breast cancer

5. DNA-Binding Properties of Cosmomycin D, an Anthracycline with Two Trisaccharide Chains

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