Bcr4 Is a Chaperone for the Inner Rod Protein in the <i>Bordetella</i> Type III Secretion System-Reference-Cited by-同舟云学术

Bcr4 Is a Chaperone for the Inner Rod Protein in the Bordetella Type III Secretion System

Published:2022-10-26 Issue:5 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Goto Masataka¹,Abe Akio¹,Hanawa Tomoko²,Suzuki Masato³,Kuwae Asaomi¹^ORCID

Affiliation:

1. Laboratory of Bacterial Infection, Graduate School of Infection Control Sciences, Kitasato University, Tokyo, Japan

2. Department of Infectious Diseases, Kyorin University School of Medicine, Tokyo, Japan

3. Antimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan

Abstract

The type III secretion system (T3SS) is a needle-like complex that projects outward from bacterial cells. Bordetella bronchiseptica uses the T3SS to inject virulence proteins into host cells. Our previous study reported that a protein named Bcr4 is essential for the secretion of virulence proteins from B. bronchiseptica bacterial cells and delivery through the T3SS.

Funder

Japan Agency for Medical Research and Development

Ministry of Education, Culture, Sports, Science and Technology

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01443-22

Reference39 articles.

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5. Assembly, structure, function and regulation of type III secretion systems